Available to order

International strain nameFVB-Tg(ACTB-tTS)1Mllo/Cnrm
Alternative namepAct-tTS
Strain typeTransgenic Strains
Allele/Transgene symbolTg(ACTB-tTS)1Mllo,
Gene/Transgene symbolTg(ACTB-tTS)1Mllo

Information from provider

ProviderMoises Mallo
Provider affiliationInstituto Gulbenkian de Ciencia
Genetic informationThe tTS molecule (a hybrid between the tetracycline repressor, tetR and the KRAB transcriptional repressor) is expressed ubiquitously under the human beta-actin promoter. The construct also contains insulator sequences from the chicken globin locus. This is a transgenic strain to be used in a dual control system to allow repression from promoters carrying tetO (tetracycline operator) sequences. It can be used to produce reversible gene inactivation from tetO-modified loci or to repress the leakiness of tetO promoters when using the tet-ON system.
Phenotypic informationThere are no defects associated to this strain.
  • Reversible gene inactivation in the mouse.;Mallo Moisés, Kanzler Benoît, Ohnemus Sabine, ;2003;Genomics;81;356-60; 12676559

Information from EMMA

Archiving centreCNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy

Literature references

  • Reversible gene inactivation in the mouse.;Mallo Moisés, Kanzler Benoît, Ohnemus Sabine, ;2003;Genomics;81;356-60; 12676559

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Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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