C57BL/6J-Cd1d1em1H/H

Status

Available to order

EMMA IDEM:14616
International strain nameC57BL/6J-Cd1d1em1H/H
Alternative nameCD1D1-LPETG-EM1-B6
Strain typeEndonuclease-mediated
Allele/Transgene symbolCd1d1em1H
Gene/Transgene symbolCd1d1

Information from provider

Provider MRC-Harwell
Provider affiliationMammalian Genetics Unit, Mary Lyon Centre at MRC Harwell
Genetic informationFor detailed information on the genetic description of this strain, please have a look at this report.
Phenotypic informationHomozygous:
not known

Heterozygous:
None reported
Breeding historyCo-isogenic on original background
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (gene matching)
  • decreased red blood cell distribution width / IMPC
  • increased circulating amylase level / IMPC
  • increased basophil cell number / IMPC
MGI phenotypes (gene matching)
  • abnormal liver morphology / MGI
  • decreased IgG level / MGI
  • arrested T cell differentiation / MGI
  • abnormal T cell activation / MGI
  • abnormal antigen presentation / MGI
  • autoimmune response / MGI
  • kidney inflammation / MGI
  • lung inflammation / MGI
  • increased susceptibility to bacterial infection / MGI
  • abnormal dendritic cell antigen presentation / MGI
  • glomerulonephritis / MGI
  • increased urine protein level / MGI
  • increased susceptibility to ischemic brain injury / MGI
  • renal interstitial fibrosis / MGI
  • decreased susceptibility to induced arthritis / MGI
  • increased anti-double stranded DNA antibody level / MGI
  • increased anti-nuclear antigen antibody level / MGI
  • decreased regulatory T cell number / MGI
  • decreased acute inflammation / MGI
  • glomerulosclerosis / MGI
  • increased blood urea nitrogen level / MGI
  • abnormal NK T cell morphology / MGI
  • decreased NK T cell number / MGI
  • abnormal NK T cell physiology / MGI
  • abnormal CD4-positive T cell differentiation / MGI
  • increased IgG3 level / MGI
  • decreased tumor necrosis factor secretion / MGI
  • decreased interferon-gamma secretion / MGI
  • decreased interleukin-2 secretion / MGI
  • abnormal interleukin-4 secretion / MGI
  • decreased interleukin-4 secretion / MGI
  • decreased physiological sensitivity to xenobiotic / MGI
  • increased susceptibility to bacterial infection induced morbidity/mortality / MGI
  • renal tubule atrophy / MGI
  • glomerular crescent / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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