- abnormal spleen morphology / IMPC
- decreased exploration in new environment / IMPC
- decreased thigmotaxis / IMPC
- small spleen / IMPC
- decreased anxiety-related response / IMPC
- abnormal behavior / IMPC
- decreased locomotor activity / IMPC
- abnormal eye morphology / IMPC
- abnormal kidney morphology / IMPC
- small kidney / IMPC
- anophthalmia / IMPC
C57BL/6NTac-Kcnt1em1H/H
Status | Available to order |
EMMA ID | EM:14629 |
International strain name | C57BL/6NTac-Kcnt1em1H/H |
Alternative name | KCNT1-R409Q-EM2-B6N |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Kcnt1em1H |
Gene/Transgene symbol | Kcnt1 |
Information from provider
Provider | MRC-Harwell |
Provider affiliation | Mammalian Genetics Unit, Mary Lyon Centre at MRC Harwell |
Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
Phenotypic information | Homozygous:not knownHeterozygous:None reported |
Breeding history | Co-isogenic on original background |
References | None available |
Homozygous fertile | not known |
Homozygous viable | not known |
Homozygous matings required | not known |
Immunocompromised | not known |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Malignant migrating focal seizures of infancy / Orphanet_293181
- Autosomal dominant nocturnal frontal lobe epilepsy / Orphanet_98784
IMPC phenotypes (gene matching)
Information on how we integrate external resources can be found here
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