C57BL/6J-Polgem1H/H
Status | Available to order |
EMMA ID | EM:14641 |
International strain name | C57BL/6J-Polgem1H/H |
Alternative name | POLG-A449T-EM1-B6 |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Polgem1H |
Gene/Transgene symbol | Polg |
Information from provider
Provider | MRC-Harwell |
Provider affiliation | Mammalian Genetics Unit, Mary Lyon Centre at MRC Harwell |
Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
Phenotypic information | Homozygous:not knownHeterozygous:None reported |
Breeding history | Co-isogenic on original background |
References | None available |
Homozygous fertile | not known |
Homozygous viable | not known |
Homozygous matings required | not known |
Immunocompromised | not known |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Alpers-Huttenlocher syndrome / Orphanet_726
- Spinocerebellar ataxia with epilepsy / Orphanet_254881
- Autosomal dominant progressive external ophthalmoplegia / Orphanet_254892
- Mitochondrial neurogastrointestinal encephalomyopathy / Orphanet_298
- Recessive mitochondrial ataxia syndrome / Orphanet_94125
- Sensory ataxic neuropathy-dysarthria-ophthalmoparesis syndrome / Orphanet_70595
- Autosomal recessive progressive external ophthalmoplegia / Orphanet_254886
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