- decreased level of surface class I molecules / MGI
- abnormal T cell differentiation / MGI
- increased susceptibility to viral infection / MGI
- abnormal level of surface class II molecules / MGI
- decreased CD8-positive, alpha-beta T cell number / MGI
- decreased single-positive T cell number / MGI
- decreased plasmacytoid dendritic cell number / MGI
- decreased dendritic cell number / MGI
- increased susceptibility to viral infection induced morbidity/mortality / MGI
- decreased central memory CD8 positive, alpha-beta T cell number / MGI
C57BL/6NTac-Stat2em1H/H
Status | Available to order |
EMMA ID | EM:14652 |
International strain name | C57BL/6NTac-Stat2em1H/H |
Alternative name | STAT2-FLOX-EM1-B6N |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Stat2em1H |
Gene/Transgene symbol | Stat2 |
Information from provider
Provider | MRC-Harwell |
Provider affiliation | Mammalian Genetics Unit, Mary Lyon Centre at MRC Harwell |
Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
Phenotypic information | Homozygous:not knownHeterozygous:None reported |
Breeding history | Co-isogenic on original background |
References | None available |
Homozygous fertile | not known |
Homozygous viable | not known |
Homozygous matings required | not known |
Immunocompromised | not known |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection / Orphanet_431166
MGI phenotypes (gene matching)
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