C57BL/6J-Syt1em1H/H
Status | Available to order |
EMMA ID | EM:14653 |
International strain name | C57BL/6J-Syt1em1H/H |
Alternative name | SYT1-F349A-EM1-B6 |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Syt1em1H |
Gene/Transgene symbol | Syt1 |
Information from provider
Provider | MRC-Harwell |
Provider affiliation | Mammalian Genetics Unit, Mary Lyon Centre at MRC Harwell |
Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
Phenotypic information | Homozygous:not knownHeterozygous:None reported |
Breeding history | Co-isogenic on original background |
References | None available |
Homozygous fertile | not known |
Homozygous viable | not known |
Homozygous matings required | not known |
Immunocompromised | not known |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Infantile hypotonia-oculomotor anomalies-hyperkinetic movements-developmental delay syndrome / Orphanet_522077
IMPC phenotypes (gene matching)
MGI phenotypes (gene matching)
- abnormal suckling behavior / MGI
- no abnormal phenotype detected / MGI
- abnormal CNS synaptic transmission / MGI
- abnormal adrenal gland physiology / MGI
- abnormal excitatory postsynaptic currents / MGI
- increased synaptic depression / MGI
- abnormal inhibitory postsynaptic currents / MGI
- dilated bile duct / MGI
- biliary cyst / MGI
- nervous system phenotype / MGI
- abnormal synaptic transmission / MGI
- abnormal miniature excitatory postsynaptic currents / MGI
- abnormal neuron physiology / MGI
- abnormal neurotransmitter secretion / MGI
- thoracoschisis / MGI
- perimembraneous ventricular septal defect / MGI
- postnatal lethality, complete penetrance / MGI
- adrenal gland cyst / MGI
- thyroid cyst / MGI
- abnormal ductus venosus valve morphology / MGI
- abnormal infrahyoid muscle connection / MGI
- abnormal coronary sinus connection / MGI
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