- malocclusion / MGI
- abnormal cell death / MGI
- abnormal foregut morphology / MGI
- absent floor plate / MGI
- absent notochord / MGI
- decreased body size / MGI
- abnormal eye development / MGI
- circling / MGI
- abnormal gait / MGI
- hunched posture / MGI
- impaired righting response / MGI
- increased circulating triglyceride level / MGI
- increased circulating free fatty acid level / MGI
- absent mesoderm / MGI
- abnormal endoderm development / MGI
- abnormal somite development / MGI
- abnormal somite shape / MGI
- decreased embryo size / MGI
- reduced female fertility / MGI
- abnormal glucose homeostasis / MGI
- postnatal lethality / MGI
- premature death / MGI
- abnormal developmental patterning / MGI
- abnormal embryonic tissue morphology / MGI
- abnormal neural tube morphology / MGI
- no abnormal phenotype detected / MGI
- abnormal primitive streak formation / MGI
- kinked neural tube / MGI
- abnormal nervous system development / MGI
- abnormal craniofacial development / MGI
- abnormal miscarriage rate / MGI
- long incisors / MGI
- abnormal rostral-caudal axis patterning / MGI
- abnormal metabolism / MGI
- abnormal paraxial mesoderm morphology / MGI
- absent estrous cycle / MGI
- absent estrus / MGI
- absent primitive node / MGI
- increased liver triglyceride level / MGI
- abnormal neuron differentiation / MGI
- mortality/aging / MGI
- neonatal lethality, incomplete penetrance / MGI
- embryonic lethality, complete penetrance / MGI
- embryonic lethality during organogenesis, complete penetrance / MGI
- abnormal primitive endoderm morphology / MGI
- decreased somite size / MGI
- fused somites / MGI
- delayed heart development / MGI
- embryonic-extraembryonic boundary constriction / MGI
- rostral body truncation / MGI
- abnormal chordamesoderm morphology / MGI
- abnormal primitive streak elongation / MGI
- increased embryonic tissue cell apoptosis / MGI
C57BL/6J-Foxa2em1H/H
Status | Available to order |
EMMA ID | EM:15131 |
International strain name | C57BL/6J-Foxa2em1H/H |
Alternative name | Foxa2-S169P-EM1-B6J |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Foxa2em1H |
Gene/Transgene symbol | Foxa2 |
Information from provider
Provider | MRC-Harwell |
Provider affiliation | Mammalian Genetics Unit, Mary Lyon Centre at MRC Harwell |
Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
Breeding history | Co-isogenic on original background |
References | None available |
Homozygous fertile | not known |
Homozygous viable | not known |
Homozygous matings required | not known |
Immunocompromised | not known |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Combined pituitary hormone deficiencies, genetic forms / Orphanet_95494
MGI phenotypes (gene matching)
Information on how we integrate external resources can be found here
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