C57BL/6J-Foxa2em1H/H

Status

Available to order

EMMA IDEM:15131
International strain nameC57BL/6J-Foxa2em1H/H
Alternative nameFoxa2-S169P-EM1-B6J
Strain typeEndonuclease-mediated
Allele/Transgene symbolFoxa2em1H
Gene/Transgene symbolFoxa2

Information from provider

Provider MRC-Harwell
Provider affiliationMammalian Genetics Unit, Mary Lyon Centre at MRC Harwell
Genetic informationFor detailed information on the genetic description of this strain, please have a look at this report.
Breeding historyCo-isogenic on original background
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (gene matching)
  • malocclusion / MGI
  • abnormal cell death / MGI
  • abnormal foregut morphology / MGI
  • absent floor plate / MGI
  • absent notochord / MGI
  • decreased body size / MGI
  • abnormal eye development / MGI
  • circling / MGI
  • abnormal gait / MGI
  • hunched posture / MGI
  • impaired righting response / MGI
  • increased circulating triglyceride level / MGI
  • increased circulating free fatty acid level / MGI
  • absent mesoderm / MGI
  • abnormal endoderm development / MGI
  • abnormal somite development / MGI
  • abnormal somite shape / MGI
  • decreased embryo size / MGI
  • reduced female fertility / MGI
  • abnormal glucose homeostasis / MGI
  • postnatal lethality / MGI
  • premature death / MGI
  • abnormal developmental patterning / MGI
  • abnormal embryonic tissue morphology / MGI
  • abnormal neural tube morphology / MGI
  • no abnormal phenotype detected / MGI
  • abnormal primitive streak formation / MGI
  • kinked neural tube / MGI
  • abnormal nervous system development / MGI
  • abnormal craniofacial development / MGI
  • abnormal miscarriage rate / MGI
  • long incisors / MGI
  • abnormal rostral-caudal axis patterning / MGI
  • abnormal metabolism / MGI
  • abnormal paraxial mesoderm morphology / MGI
  • absent estrous cycle / MGI
  • absent estrus / MGI
  • absent primitive node / MGI
  • increased liver triglyceride level / MGI
  • abnormal neuron differentiation / MGI
  • mortality/aging / MGI
  • neonatal lethality, incomplete penetrance / MGI
  • embryonic lethality, complete penetrance / MGI
  • embryonic lethality during organogenesis, complete penetrance / MGI
  • abnormal primitive endoderm morphology / MGI
  • decreased somite size / MGI
  • fused somites / MGI
  • delayed heart development / MGI
  • embryonic-extraembryonic boundary constriction / MGI
  • rostral body truncation / MGI
  • abnormal chordamesoderm morphology / MGI
  • abnormal primitive streak elongation / MGI
  • increased embryonic tissue cell apoptosis / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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