Available to order

International strain nameC57BL/6N-Fshrtm1.2(cre)Ics/Ics
Alternative nameFshrtm1.2(cre)Ics
Strain typeTargeted Mutant Strains : Knock-in
Allele/Transgene symbolFshrtm1.2(cre)Ics
Gene/Transgene symbolFshr

Information from provider

Provider ICS, Institut Clinique de la Souris
Provider affiliationICS, Institut Clinique de la Souris
Genetic informationThis line was obtained by crossing Fshrtm1.1(cre/ERT2)Ics animals with the C57BL/6NTac-Gt(ROSA)26Sor-tm2(CAG-flpo,-EYFP)Ics flp ubiquitous deleter (EMMA strain ID EM:05490), resulting in an IRES-cre-F3 sequence located into the 3' UTR region of the Fshr gene. The pure C57BL/6N background was maintained for all breeding steps. Efficiency of deletion was confirmed by crossing this line with the fluorescent reporter of cre expression Gt(ROSA)26Sor-tm4(ACTB-tdTomato,-EGFP)Luo. A specific EGFP signal was observed in the ovaries and no signal was observed in the control organ (liver). Analysis of mRNA expression showed that tm1.2 allele (cre probe) mRNA is also expressed at an expected level in the ovaries. For detailed information on the genetic description of this strain, please have a look at this report.
Phenotypic informationHomozygous:

Breeding historyC57BL/6N inbred (3 generations).
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno

Information from EMMA

Archiving centreICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

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Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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