Available to order

International strain nameBALB/cN-Prg2tm2(RFP657/cre/ERT2)Ics/Ics
Alternative namePrg2tm2(RFP657/cre/ERT2)Ics
Strain typeEndonuclease-mediated
Allele/Transgene symbolPrg2tm2(RFP657/cre/ERT2)Ics
Gene/Transgene symbolPrg2

Information from provider

Provider ICS, Institut Clinique de la Souris
Provider affiliationICS, Institut Clinique de la Souris
Genetic informationThis line was obtained by modification of BA3 BALB/cN embryonic stem cells. A 5.6 kb trap cassette was inserted by homologous recombination in ES cells in the intronic region of Prg2 located between exon 2 and exon 3. This cassette contains intron 1 and partial exon sequence of En2 to act as splice donor site, a LF2A (2A self-cleaving peptide) sequence that can induce ribosomal skipping during translation, a mutated TagRFP657 far-red monomeric fluorescent protein sequence, a T2A sequence and a dual cre-F3-ERT2-F3 cassette that allow expression of creERT2 or cre (if crossed with a flp deleter) and a selection cassette. The pPGK-Neo selection cassette flanked by rox attachment sites was not removed. FACS analysis showed efficient and specific cre expression in spleen eosinophils. TagRFP657 is not detected due to a mutation in its cDNA. For detailed information on the genetic description of this strain, please have a look at this report.
Phenotypic informationHomozygous:

Breeding historyBALB/cN inbred (4 generations).
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno

Information from EMMA

Archiving centreICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France

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Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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