C57BL/6J-Flncem1H/H
Status | Available to order |
EMMA ID | EM:15586 |
International strain name | C57BL/6J-Flncem1H/H |
Alternative name | C57BL/6J-Flncem1H/H |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Flncem1H |
Gene/Transgene symbol | Flnc |
Information from provider
Provider | MRC, Medical Research Council |
Provider affiliation | Mammalian Genetics Unit, Mary Lyon Centre at MRC Harwell |
Genetic information | As reported by Mouse Genome Informatics, Flnc, a protein coding gene, codes for filamin C and is associated with myofibrillar myopathy in both mice and humans and distal myopathy, and hypertrophic cardiomypathy in humans. This is a CRISPR/Cas9 induced targeted deletion of exon 40 of the Flnc gene via cytoplasmic injection of CRISPR/Cas9 reagents into 2-cell stage embryos. |
Phenotypic information | Homozygous:To be confirmedHeterozygous:To be confirmed |
Breeding history | Incepient congenic on maintained background |
References | None available |
Homozygous fertile | not known |
Homozygous viable | not known |
Homozygous matings required | not known |
Immunocompromised | not known |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
IMPC phenotypes (gene matching)
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