B6;D2-Tg(Ttr-cre/Esr1*)1Vco/Orl

Status

Available to order

EMMA IDEM:01713
International strain nameB6;D2-Tg(Ttr-cre/Esr1*)1Vco/Orl
Alternative nameTTR-Cre ind
Strain typeTransgenic Strains
Allele/Transgene symbolTg(Ttr-cre/Esr1*)1Vco,
Gene/Transgene symbolTg(Ttr-cre/Esr1*)1Vco

Information from provider

ProviderMireille Vasseur-Cognet
Provider affiliationInstitut Cochin, INSERM U567, Faculté de Cochin, GDPM
Genetic informationGene fusion of the cre recombinase and mouse estrogen receptor hormone-binding domain coding sequences, under the control of a mouse transthyretin promoter.
Phenotypic informationNo defects.
Breeding historyTransgenic mice have always been bred as heterozygotes with wild-type mice.
References
  • A tamoxifen-inducible chimeric Cre recombinase specifically effective in the fetal and adult mouse liver.;Tannour-Louet Mounia, Porteu Arlette, Vaulont Sophie, Kahn Axel, Vasseur-Cognet Mireille, ;2002;Hepatology (Baltimore, Md.);35;1072-81; 11981757
  • Loss of the anaphase-promoting complex in quiescent cells causes unscheduled hepatocyte proliferation.;Wirth Karin G, Ricci Romeo, Giménez-Abián Juan F, Taghybeeglu Shahryar, Kudo Nobuaki R, Jochum Wolfram, Vasseur-Cognet Mireille, Nasmyth Kim, ;2004;Genes & development;18;88-98; 14724179

Information from EMMA

Archiving centreInstitut de Transgenose, INTRAGENE, Orléans, France
Animals used for archivingheterozygous C57BL/6J, wild-type C57BL/6J
Breeding at archiving centreMales are transgenic: some of them are perhaps homozygous but they can be discriminated by PCR.

Literature references

  • A tamoxifen-inducible chimeric Cre recombinase specifically effective in the fetal and adult mouse liver.;Tannour-Louet Mounia, Porteu Arlette, Vaulont Sophie, Kahn Axel, Vasseur-Cognet Mireille, ;2002;Hepatology (Baltimore, Md.);35;1072-81; 11981757
  • Loss of the anaphase-promoting complex in quiescent cells causes unscheduled hepatocyte proliferation.;Wirth Karin G, Ricci Romeo, Giménez-Abián Juan F, Taghybeeglu Shahryar, Kudo Nobuaki R, Jochum Wolfram, Vasseur-Cognet Mireille, Nasmyth Kim, ;2004;Genes & development;18;88-98; 14724179

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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