B6;129-Rr152tm3.1Cog/Orl
| Status | Available to order |
| EMMA ID | EM:00212 |
| Citation information | RRID:IMSR_EM:00212 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129-Rr152tm3.1Cog/Orl |
| Alternative name | delta hs3b/hs4 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Rr152tm3.1Cog |
| Gene/Transgene symbol | Rr152 |
Information from provider
| Provider | Michel Cogne |
| Provider affiliation | UMR CNRS 6101, Universite de Limoges |
| Genetic information | Deletion of the hs3b and hs4 transcriptional enhancers within the Igh locus, 3 prime-regulatory region. |
| Phenotypic information | Immunoglobulin IgG2b, IgG2a, IgG3, IgE and IgA class switching defects. |
| Breeding history | genetic background: 129 x C57BL/6 |
| References |
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Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Literature references
- Localization of the 3' IgH locus elements that effect long-distance regulation of class switch recombination.;Pinaud E, Khamlichi A A, Le Morvan C, Drouet M, Nalesso V, Le Bert M, Cogné M, ;2001;Immunity;15;187-99; 11520455