STOCK Hnf4atm1(cre)Sdv/H


Available to order

International strain nameSTOCK Hnf4atm1(cre)Sdv/H
Alternative nameHnf4 cre
Strain typeTargeted Mutant Strains : Knock-in
Allele/Transgene symbolHnf4atm1(cre)Sdv,
Gene/Transgene symbolHnf4a

Information from provider

ProviderElizabeth Robertson
Provider affiliationSir William Dunn School of Pathology, University of Oxford
Genetic informationStrain carries a knock-in of cre recombinase into the Hnf4a locus. Strain expresses Cre efficiently in the hepatocytes of the developing liver to allow conditional gene deletion or activation in this lineage.
Phenotypic informationHomozygous lethal at mid gestation due to defects in liver formation.
Breeding historyBackcrossed on a 129S/SvEv background.
ReferencesNone available
Homozygous fertileno
Homozygous viableno
Homozygous matings requiredno
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

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Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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