STOCK Tg(Myh6-tTA)6Smbf/Cnrm


Available to order

International strain nameSTOCK Tg(Myh6-tTA)6Smbf/Cnrm
Alternative namealphaMHC-tTA
Strain typeTransgenic Strains
Allele/Transgene symbolTg(Myh6-tTA)6Smbf,
Gene/Transgene symbolTg(Myh6-tTA)6Smbf

Information from provider

ProviderGlenn Fishman
Provider affiliationNYU Langone Medical Center
Genetic informationAlpha-MHC-tTA mice contain the cardiac specific alpha-myosin heavy chain promoter driving the tetracycline transactivator (tTA). The murine line expresses tTA transactivator specifically in cardiomyocytes. This allows inducible expression of TetO responder gene in the heart with the tet-off system.
Phenotypic informationNo phenotype defect detected.
Breeding historyThey have been backcrossed to FVB.
  • Conditional transgene expression in the heart.;Yu Z, Redfern C S, Fishman G I, ;1996;Circulation research;79;691-7; 8831492
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno

Information from EMMA

Archiving centreCNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy
Animals used for archivingheterozygous FVB, wild-type FVB/N
Stage of embryos2-cell

Literature references

  • Conditional transgene expression in the heart.;Yu Z, Redfern C S, Fishman G I, ;1996;Circulation research;79;691-7; 8831492

Information on how we integrate external resources can be found here



Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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