- small kidney / MGI
- absent incus / MGI
- neonatal lethality, complete penetrance / MGI
- abnormal malleus morphology / MGI
- increased cochlear inner hair cell number / MGI
- increased cochlear outer hair cell number / MGI
- abnormal stapes morphology / MGI
- abnormal incudomalleolar joint morphology / MGI
- absent kidney / MGI
- decreased corpus callosum size / MGI
- abnormal cerebral cortex morphology / MGI
- absent dentate gyrus / MGI
- abnormal Ammon gyrus morphology / MGI
- abnormal lateral ventricle morphology / MGI
- dilated third ventricle / MGI
- small olfactory bulb / MGI
- abnormal hippocampal fimbria morphology / MGI
- abnormal hippocampal fornix morphology / MGI
- decreased anterior commissure size / MGI
- abnormal cerebral hemisphere morphology / MGI
B6.129-Emx2tm1Pgr/Cnrm
Status | Available to order |
EMMA ID | EM:00065 |
International strain name | B6.129-Emx2tm1Pgr/Cnrm |
Alternative name | Emx2-KO |
Strain type | Targeted Mutant Strains : Knock-out |
Allele/Transgene symbol | Emx2tm1Pgr, |
Gene/Transgene symbol | Emx2 |
Information from provider
Provider | Peter Gruss |
Provider affiliation | Max Planck Inst. Biophysical Chemistry |
Phenotypic information | Homozygous embryos die postnatally because of severe urogenital alterations. Emx2 is required for the development of several forebrain structures. |
References |
|
Information from EMMA
Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
MGI phenotypes (allele matching)
Literature references
- Dentate gyrus formation requires Emx2.;Pellegrini M, Mansouri A, Simeone A, Boncinelli E, Gruss P, ;1996;Development (Cambridge, England);122;3893-8; 9012509
Information on how we integrate external resources can be found here
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).