Available to order

International strain nameC57BL/6J-Tg(tetO-ARAP1,-luc)1Rttr/H
Alternative nameArap1-tg
Strain typeTransgenic Strains
Allele/Transgene symbolTg(tetO-ARAP1,-luc)1Rttr
Gene/Transgene symbolTg(tetO-ARAP1,-luc)1Rttr

Information from provider

ProviderGuy Rutter
Provider affiliationSection of Cell Biology, Department of Medicine, Imperial College London
Genetic informationInsertion of a coding cassette under the control of a bidirectional tetracycline-regulated promoter driving the expression of both human flag-ARAP1 and firefly luciferase. Vector used for the subcloning of the transgene incorporated on this strain: pBI-L Vector PT3069-5 GenBank Accession No.:U89934 Catalog No. 631005.
Phenotypic informationHomozygous:

Overexpression of the transgene after crossing with mice expressing the reverse tetracycline transactivator and given doxycycline in drinking water (possibility of inducing overexpression in a specific tissue).
Breeding historyFounder crossed with wild-type C57BL/6J to obtain F1; F1 crossed with wild-type C57BL/6J to obtain F2 to ensure the stability of the line (only one insertion site in the genome).
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

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Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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