This project has received funding from the European Union’s Horizon Europe research and innovation programme under grant agreement No 101131669.
INFRAPLUS
Enhancing and Evolving INFRAFRONTIER Disease Modelling Capacity to Enable Breakthrough Research

Photo credit: NTB
Project Period:
1 June 2024 – 31 May 2027
Total Cost:
€5M
Grant Agreement:
101131669
Coordinated by
INFRAFRONTIER ERIC
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Project Description
INFRAPLUS aims to expand INFRAFRONTIER’s capacity for human disease modelling, refine its service portfolio by reducing animal usage and developing alternative cellular models, and optimise the use of resources. INFRAPLUS seeks to achieve several objectives: Developing national node capacities and expertise for providing innovative in vivo, in vitro and preclinical services, developing novel model systems and services to meet the demands of existing and novel user communities, and reducing environmental impact.

INFRAPLUS’s objectives
INFRAPLUS Consortium
12 European countries and Canada
18 institutions
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INFRAPLUS Services
INFRAPLUS is developing pilot services for scientists worldwide using mouse models for fundamental and translational research. These services enhance the reliability and translational value of rodent models by ensuring genetic accuracy and functional validation.
Want free access to these services? Stay tuned for the open calls we’ll launch throughout the project.
Work Packages
WP | Title | Lead Partner |
WP1 | Human Disease Modelling using Innovative in vivo Technologies, Models and Services | HMGU & PHENOMIN-ICS |
WP2 | Development of in vitro Animal Models and Services | Karolinska Institutet & Vetmeduni |
WP3 | Development of Disease Screens and Evaluation of Preclinical Pipelines | CCP & Alexander Fleming |
WP4 | Data Management, Enrichment and Analysis | UOulu & CNR |
WP5 | Enhancing Operational Expertise for Modelling Human Diseases | UKRI |
WP6 | Animal Welfare, Sustainable Practices and Ethical Considerations | CNB-CSIC |
WP7 | Dissemination, Exploitation, and Outreach | INFRAFRONTIER ERIC |
WP8 | Project Coordination & Management | INFRAFRONTIER ERIC |
INFRAFRONTIER Conferences
Thanks to the INFRAPLUS project, the INFRAFRONTIER Conferences are back! Join us for this exciting series of three annual conferences taking place throughout the duration of the project. Don’t miss this opportunity to connect with experts and stay at the forefront of disease modelling and human disease research!