IPAD-MD project (Research Infrastructure for Phenotyping, Arching and Distribution of Mouse Diseases Models)  addressed the global cooperation and coordination between INFRAFRONTIER and complementary research infrastructures world-wide, contributing to the global effort of IMPC. IPAD-MD will focused on key stakeholder involvement.

IPAD-MD organized a series of workshops aiming at:

  • Improving access to common  INFRAFRONTIER and IMPC resources
  • Aligning scientific strategy with international research agendas
  • Engaging key stakeholders to improve INFRAFRONTIER and IMPC resources and services
  • Coordinating globally the development of innovative technology solutions

The deliverables from the IPAD-MD project are publically available here.



IPAD-MD Topics

Topic I. Global Access to Common Resources
Keywords: MTAs, IP and licensing models, repositories sustainable funding, material shipping issues, standards & nomenclature   

Topic II. Key Stakeholder Engagement
Keywords: Resource usability, (priorisation) mouse disease models, visibility of resources and services

Topic III. Innovative Technology Solutions
Keywords: (optimisation) existing pipelines, common standards, reliability and interoperability, big data & data services


Cross-cutting themes

Animal welfare
Outreach to Africa
Communications & Dissemination

Stakeholders Meetings

2015: Kick-Off meeting, July 21-22, Munich, Germany

Agenda & Minutes

IPAD-MD KO 07.2015


2016: Industry & Innovation Worskhop, 28-29 June, Munich, Germany 

Agenda & List of Participants (17.06.2016) 

Abstract Book (16.06.2016)

Exhibition area  - Floor plan (20.06.2016)

Practical Information

Industry & Innovation Workshop Report (D2.1; 28.06.2016)


Literature collection to support the panel discussions

Panel 1: Impact of CRISPR technology on repositories, IT & animal welfare

Doudna & Charpentier. 2014. Genome editing The new frontier of genome engineering with CRISPR-Cas9 PMID: 25430774

Dow. 2015. Modeling Disease In Vivo with CRISPR/Cas9. PMID: 26432018  

Hsu et al. 2014. Development and applications of CRISPR-Cas9 for genome engineering.PMID: 24906146 

Ledford. 2015. CRISPR, the disruptor. PMID: 26040877


Panel 2: Impact of rodents as model of human diseases

Collins & Tabak. 2014. NIH  plans to enhance reproducibitlity. PMID: 24482835

Everitt. 2014. The future of preclinical animal models in pharmaceutical discovery and developments: a need to bring in cerebro to the in vivo discussions PMID: 25351920

Ioannidis JPA. 2014. How to make more published research true PMID: 25334033

Justice & Dhilon. 2016. Using the mouse to model human disease: increasing validity and reproducibility. PMID: 26839397

Macleod et al  2014. Biomedical research: increasing value, reducing waste PMID: 24411643

Perrin. 2014. Make mouse studies work. PMID: 24678540

Prinz et al., 2011. Believe it or not: how much can we rely on published data on potential drug targets? PMID: 21892149

Steckler. 2015. Preclinical data reproducibility for R&D - the challenge for neuroscience. PMID: 25585680 

Vandamme. 2015. Rodent models for human diseases. PMID: 25823811

van der Worp et al., 2010. Can animal models of disease reliably inform human studies? PMID: 20361020 


2017: INFRAFRONTIER / IMPC Stakeholder Meeting

Advancing Personalised Medicine with Animal Models

November 14th to 16th, 2017   -   Athens, Greece  -  Royal Olympic Hotel

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2018: INFRAFRONTIER / IMPC Stakeholder Meeting 2018 

Advancing Rare Disease Research and Gene Therapy Applications with Animal Models

December 3rd to 4th, 2018   -   Munich, Germany  -  Hilton Munich Park Hotel

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2019: INFRAFRONTIER / IMPC Conference 2019

Genetic Variation, Big Data and Ageing

June 3rd to 5th, 2019   -   Helsinki, Finland

Read more


Expert Group Meetings


Standards & Technology Expert Group Meeting - Phenotyping, September 14-15, Seoul, Korea  & Archiving, November 18, Rome, Italy

Meeting report  (D6.1, 11.12.2015)

Data & Resources Expert Group Meeting, October 27-28, Hinxton, UK

Meeting report  (D7.1, 01.12.2015) 

 IPAD-MD WS D&R 10.2015


Standards & Technology Expert Group Meeting (WP6) : 'Genome Editing Workshop' at  IMPC - INFRAFRONTIER Strasbourg meeting, 20-22 April 2016

Meeting report  (D6.2, 20.04.2016)

Data & Resources Expert Group Meeting (WP7): Improving Curation and Annotation Tooling for Animal Models of Rare Disease, 08-09 December 2016, Freising, Germany

Workshop goals

  1. Facilitate communication between curators that have an interest in annotating animal models of human disease
  2. Discuss the strengths and weaknesses of curatorial resources (ontologies, tools, etc)
  3. Investigate synergies between groups to accelerate annotation of rare disease models

Meeting report  (D7.2, 08.12.2016)



INFRAFRONTIER / IMPC Epigenetics Workshop 2018 

5th December 2018, Munich, Germany

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INFRAFRONTIER Forward Genetics Panel Discussion at IMGC 2018

13th November 2018, Rio Grande, Puerto Rico

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INFRAFRONTIER Workshop on Rare Diseases Data Integration at ASHG 2019

15th October, Houston, USA

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INFRAFRONTIER Workshop on Sustainability of Mouse Informatics Resources at IMGC 2019

25-26th September 2019, Strasbourg, France

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INFRAFRONTIER / IMPC Machine Learning Hackathon

23-24th January 2019, Munich, Germany

Read report

IPAD-MD  has received funding  from European Union's Horizon 2020 research and innovation programme under Grant Agreement number 653961.