MGI phenotypes (allele matching)
STOCK Pde6batrd2/H
| Status | Available to order |
| EMMA ID | EM:00142 |
| International strain name | STOCK Pde6batrd2/H |
| Alternative name | Pde6b |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Pde6batrd2, |
| Gene/Transgene symbol | Pde6b |
Information from provider
| Provider | Caroline Thaung |
| Provider affiliation | MRC Mammalian Genetics Unit |
| Phenotypic information | Mice with this mutation have slow onset retinal degeneration. |
| Breeding history | Initially crossed to C57BL/6J to recover the mutation and then crossed to C3H/HeH and intercrossed to remove the retinal degeneration gene carried by C3H/HeH. |
| References |
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Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI allele-associated human disease models
Orphanet associated rare diseases, based on orthologous gene matching
- Retinitis pigmentosa / Orphanet_791
- Congenital stationary night blindness / Orphanet_215
Literature references
- A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.;Nolan P M, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray I C, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson J A, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel K P, Voegeling S, Guenet J L, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher E M, Martin J, Rastan S, Brown S D, Hunter J, ;2000;Nature genetics;25;440-3; 10932191