STOCK Foxq1sa M54b/Foxq1+ M54b+/H

Status

Available to order

EMMA IDEM:01849
Citation informationRRID:IMSR_EM:01849 

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International strain nameSTOCK Foxq1sa M54b/Foxq1+ M54b+/H
Alternative nameM54B
Strain typeInduced Mutant Strains : Chemically-induced
Allele/Transgene symbolM54b, Foxq1sa
Gene/Transgene symbolM54b, Foxq1

Information from provider

ProviderRuth Arkell
Provider affiliationMRC Mammalian Genetics Unit
Phenotypic informationEmbryonic lethal - not fully penetrant. Possible craniofacial abnormality. No obvious phenotype in mutant mice which survive to weaning or adulthood.
References
  • A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.;Nolan P M, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray I C, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson J A, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel K P, Voegeling S, Guenet J L, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher E M, Martin J, Rastan S, Brown S D, Hunter J, ;2000;Nature genetics;25;440-3; 10932191

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

MGI phenotypes (allele matching)
  • shiny fur / MGI
  • abnormal coat appearance / MGI
  • abnormal hair growth / MGI
  • abnormal hair shaft morphology / MGI
  • impaired natural killer cell mediated cytotoxicity / MGI
MGI phenotypes (gene matching)
  • shiny fur / MGI
  • abnormal head morphology / MGI
  • decreased digestive secretion / MGI
  • abnormal lymphocyte cell number / MGI
  • abnormal brain development / MGI
  • abnormal coat appearance / MGI
  • abnormal hair growth / MGI
  • abnormal hair texture / MGI
  • abnormal response/metabolism to endogenous compounds / MGI
  • abnormal hair shaft morphology / MGI
  • abnormal hair cortex morphology / MGI
  • abnormal hair medulla / MGI
  • impaired natural killer cell mediated cytotoxicity / MGI
  • embryonic lethality during organogenesis, incomplete penetrance / MGI
  • lethality throughout fetal growth and development, incomplete penetrance / MGI

Literature references

  • A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.;Nolan P M, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray I C, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson J A, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel K P, Voegeling S, Guenet J L, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher E M, Martin J, Rastan S, Brown S D, Hunter J, ;2000;Nature genetics;25;440-3; 10932191

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Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

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