MGI phenotypes (allele matching)
STOCK Mut1544/H
| Status | Available to order |
| EMMA ID | EM:01954 |
| Citation information | RRID:IMSR_EM:01954 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Mut1544/H |
| Alternative name | MUT/1544 |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Mut1544 |
| Gene/Transgene symbol | Mut1544 |
Information from provider
| Provider | Bruce Cattanach |
| Provider affiliation | MRC Harwell, Didcot, Oxon, OX11 0RD |
| Phenotypic information | Heterozygotes have a bruised appearance at birth with bloody areas beneath the skin, most common around the belly and abdomen, some around the neck and back legs. Most also have a domed head. Penetrance of the mutation is slightly reduced, but estimated to be over 70%. Affected offspring are about 20% lighter than normal sibs at birth, and about 35% lighter than wild-type gender matched sibs at weaning. Viability of affected offspring between birth and weaning is estimated to be about 75%. Average litter size of heterozygous females is reduced (estimate: 4.9). Homozygotes: opening data indicate that they probably die by early post implantation, with a large proportion dying pre-implantation. |
| Breeding history | Original background: (C3H/HeH x 101/H) x PT. Maintained background: C3H/HeH x 101/H. Breeding History: Backcrossed to C3H/HeH for several generations. |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |