IMPC phenotypes (allele matching)
C57BL/6NTac-Bmp7tm1a(EUCOMM)Hmgu/H
| Status | Available to order |
| EMMA ID | EM:04863 |
| Citation information | RRID:IMSR_EM:04863 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6NTac-Bmp7tm1a(EUCOMM)Hmgu/H |
| Alternative name | HEPD0510_3_C07 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Bmp7tm1a(EUCOMM)Hmgu |
| Gene/Transgene symbol | Bmp7 |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
|
Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This mouse line originates from EUCOMM ES clone HEPD0510_3_C07. For further details on the construction of this clone see the page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
| Animals used for archiving | heterozygous C57BL/6NTac males |
| Breeding at archiving centre | Chimeras were mated to C57BL/6NTac USA and maintained on this background thereafter. |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal cochlea morphology / MGI
- delayed bone ossification / MGI
- decreased bone mineral density / MGI
- abnormal basioccipital bone morphology / MGI
- abnormal basisphenoid bone morphology / MGI
- cleft palate / MGI
- growth retardation of molars / MGI
- abnormal vertebrae morphology / MGI
- rib bifurcation / MGI
- rib fusion / MGI
- abnormal sternum morphology / MGI
- abnormal xiphoid process morphology / MGI
- abnormal hair follicle morphology / MGI
- abnormal craniofacial morphology / MGI
- abnormal cranium morphology / MGI
- abnormal maxilla morphology / MGI
- abnormal mandible morphology / MGI
- abnormal kidney development / MGI
- hydroureter / MGI
- polydactyly / MGI
- kinked tail / MGI
- tremors / MGI
- exencephaly / MGI
- decreased body weight / MGI
- decreased body size / MGI
- abnormal eye development / MGI
- abnormal lens vesicle development / MGI
- anophthalmia / MGI
- microphthalmia / MGI
- impaired coordination / MGI
- abnormal apical ectodermal ridge morphology / MGI
- premature death / MGI
- abnormal vibrissa morphology / MGI
- abnormal tooth morphology / MGI
- abnormal digit morphology / MGI
- abnormal axial skeleton morphology / MGI
- no abnormal phenotype detected / MGI
- abnormal cricoid cartilage morphology / MGI
- abnormal thyroid cartilage morphology / MGI
- abnormal semicircular canal morphology / MGI
- abnormal molar morphology / MGI
- small kidney / MGI
- abnormal sacral vertebrae morphology / MGI
- abnormal hyoid bone morphology / MGI
- aphakia / MGI
- abnormal soft palate morphology / MGI
- abnormal alisphenoid bone morphology / MGI
- decreased rib number / MGI
- renal hypoplasia / MGI
- dilated renal glomerular capsule / MGI
- kidney cysts / MGI
- abnormal hard palate morphology / MGI
- abnormal craniofacial development / MGI
- decreased fetal size / MGI
- small pterygoid bone / MGI
- small basisphenoid bone / MGI
- basisphenoid bone foramen / MGI
- decreased renal glomerulus number / MGI
- abnormal maxillary shelf morphology / MGI
- broad limb buds / MGI
- fusion of vertebral bodies / MGI
- decreased lumbar vertebrae number / MGI
- xiphoid process foramen / MGI
- abnormal nasal capsule morphology / MGI
- abnormal distal convoluted tubule morphology / MGI
- absent upper incisors / MGI
- abnormal retinal pigmentation / MGI
- abnormal middle ear ossicle morphology / MGI
- eyelids fail to open / MGI
- abnormal retinal pigment epithelium morphology / MGI
- abnormal renal glomerulus morphology / MGI
- cardiovascular system phenotype / MGI
- skeleton phenotype / MGI
- abnormal skeleton morphology / MGI
- retinal pigment epithelium atrophy / MGI
- decreased molar number / MGI
- asymmetric sternocostal joints / MGI
- abnormal sternocostal joint morphology / MGI
- polycystic kidney / MGI
- abnormal vibrissa number / MGI
- decreased birth weight / MGI
- palatal shelf hypoplasia / MGI
- palatal shelves fail to meet at midline / MGI
- hair follicle outer root sheath hyperplasia / MGI
- abnormal kidney mesenchyme morphology / MGI
- postnatal lethality, complete penetrance / MGI
- neonatal lethality, incomplete penetrance / MGI
- preweaning lethality, complete penetrance / MGI
- decreased nephron number / MGI
- absent metanephric mesenchyme / MGI
- short rostral-caudal axis / MGI
- small Meckel's cartilage / MGI
- abnormal lower incisor morphology / MGI
- abnormal nasal septum cartilage morphology / MGI
- abnormal temporal bone petrous part morphology / MGI
- absent thyroid cartilage / MGI
- absent cricoid cartilage / MGI