- cleft palate / IMPC
- abnormal craniofacial morphology / IMPC
- abnormal cranium morphology / IMPC
- abnormal snout morphology / IMPC
- decreased body length / IMPC
- abnormal eyelid morphology / IMPC
- abnormal embryo size / IMPC
- abnormal digit morphology / IMPC
- short tibia / IMPC
- small adrenal glands / IMPC
- abnormal facial morphology / IMPC
- abnormal bone structure / IMPC
- decreased lean body mass / IMPC
- facial cleft / IMPC
- decreased bone mineral content / IMPC
- preweaning lethality, complete penetrance / IMPC
- abnormal head shape / IMPC
- abnormal head size / IMPC
- increased or absent threshold for auditory brainstem response / IMPC
C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Ieg
Status | Available to order |
EMMA ID | EM:08100 |
International strain name | C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Ieg |
Alternative name | EPD0045_1_B11 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Nxntm1b(EUCOMM)Wtsi, |
Gene/Transgene symbol | Nxn |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH) |
Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH) |
Genetic information | This mouse line originates from EUCOMM ES clone EPD0045_1_B11. For further details on the construction of this clone see the page at the IMPC portal. The critical exon(s) were flanked by loxP sites, and subsequent cre expression excised this critical sequence resulting in a knockout reporter allele (Gt(ROSA)26Sor |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Animals used for archiving | heterozygous C57BL/6NTacUSA |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Autosomal recessive Robinow syndrome / Orphanet_1507
IMPC phenotypes (allele matching)
MGI phenotypes (allele matching)
Information on how we integrate external resources can be found here
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