xxxGnoto / Axenic Facility of the Instituto Gulbenkian de Ciência, Oeiras, Portugal
The Gnoto / Axenic Facility is part of the core animal facility of the Instituto Gulbenkian de Ciência (IGC) in Oeiras, Portugal. The IGC mouse facility is partitioned into 5 independent areas, each with a specific bio-containment level, including germ-free and strict SPF. The facility hosts about 50,000 mice that cover close to a 100 different inbred strains, available to in-house and associated research groups and visiting scientists. Production and experimental areas are designed to serve active research in various fields of biology (development, neurobiology, infectious diseases, immunology, and genetics). Ongoing scientific projects at the IGC involving the Gnoto / Axenic Facility are related to studies of immuno-compromised mice.
The Gnoto / Axenic Facility is adapted for breeding and experimentation purposes. Rigid and flexible Isolators, transfer chambers and containers are equipped with the Double Door Rapid Transfer Port (DPTE®), a user-friendly and safe connecting system for introducing and removing equipment and other materials to and from sterile isolators. Like other research facilities at the IGC, the Gnoto / Axenic Facility is available to scientists worldwide upon agreement from the Institute’s Director. Moreover, scientists who want to work with these mice can be temporarily hosted at the Institute’s laboratories if they wish to conduct their own experiments.