- preweaning lethality, complete penetrance / IMPC
C57BL/6-Atm1Brd Lpar1tm1b(EUCOMM)Wtsi/Flmg
Status | Available to order |
EMMA ID | EM:10041 |
International strain name | C57BL/6-Atm1Brd Lpar1tm1b(EUCOMM)Wtsi/Flmg |
Alternative name | B6-Lpar1 |
Strain type | Targeted Mutant Strains : Knock-out |
Allele/Transgene symbol | Lpar1tm1b(EUCOMM)Wtsi, |
Gene/Transgene symbol | Lpar1 |
Information from provider
Provider | Vassilis Aidinis |
Provider affiliation | BSRC Alexander Fleming |
Genetic information | This allele was derived from the B6-Lpar1tm1a(EUCOMM)Wtsi/Flmg line (EMMA strain EM:09092), by removing the loxP-flanked neomycin selection cassette and exon 3 (2nd coding exon; ENSMUSE00001261995) of Lpar1 via cre-mediated recombination. The resulting allele is expressing lacZ under the control of the Lpar1 promoter. Absence of the neomycin cassette and exon 3 was confirmed by PCR. |
Phenotypic information | Homozygous:No overt phenotypeHeterozygous:No overt phenotype |
References | None available |
Homozygous fertile | not known |
Homozygous viable | not known |
Homozygous matings required | no |
Immunocompromised | no |
Information from EMMA
Archiving centre | B.S.R.C. Alexander Fleming, Vari, Greece |
Animals used for archiving | heterozygous C57BL/6 |
Disease and phenotype information
IMPC phenotypes (allele matching)
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