IMPC phenotypes (gene matching)
B6(Cg)-Atm1Brd Lpar1tm1d(EUCOMM)Wtsi/Flmg
| Status | Available to order |
| EMMA ID | EM:10057 |
| Citation information | RRID:IMSR_EM:10057 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6(Cg)-Atm1Brd Lpar1tm1d(EUCOMM)Wtsi/Flmg |
| Alternative name | B6-Lpar1 tm1d(EUCOMM)Wtsi/Flmg |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Lpar1tm1d(EUCOMM)Wtsi |
| Gene/Transgene symbol | Lpar1 |
Information from provider
| Provider | Vassilis Aidinis |
| Provider affiliation | BSRC Alexander Fleming |
| Genetic information | This allele was derived from the B6-Lpar1tm1c(EUCOMM)Wtsi/Flmg line (EMMA strain EM:09947), by removing the loxP-flanked exon 3 (2nd coding exon; ENSMUSE00001261995) of Lpar1 via cre recombinase-mediated recombination. The resulting allele is a full knockout of Lpar1. The absence of exon 3 was confirmed by PCR. |
| Phenotypic information | Homozygous:No overt phenotypeHeterozygous:No overt phenotype |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | B.S.R.C. Alexander Fleming, Vari, Greece |
| Animals used for archiving | heterozygous C57BL/6 males |
Disease and phenotype information
MGI phenotypes (gene matching)
- decreased bone mineral density / MGI
- abnormal craniofacial morphology / MGI
- short snout / MGI
- exencephaly / MGI
- abnormal Schwann cell morphology / MGI
- decreased Schwann cell number / MGI
- decreased body height / MGI
- decreased body weight / MGI
- decreased body size / MGI
- ocular hypertelorism / MGI
- hypoactivity / MGI
- abnormal suckling behavior / MGI
- postnatal growth retardation / MGI
- increased dopamine level / MGI
- hemorrhage / MGI
- abnormal sciatic nerve morphology / MGI
- nervous system phenotype / MGI
- long incisors / MGI
- abnormal serotonin level / MGI
- abnormal amino acid level / MGI
- decreased body mass index / MGI
- decreased prepulse inhibition / MGI
- decreased total body fat amount / MGI
- postnatal lethality, incomplete penetrance / MGI
- neonatal lethality, incomplete penetrance / MGI
- perinatal lethality, incomplete penetrance / MGI
- decreased body fat mass / MGI