STOCK Aviltm1(HBEGF)Phep/Cnrm
| Status | Available to order |
| EMMA ID | EM:10409 |
| International strain name | STOCK Aviltm1(HBEGF)Phep/Cnrm |
| Alternative name | Avil-iDTR |
| Strain type | Targeted Mutant Strains : Knock-in |
| Allele/Transgene symbol | Aviltm1(HBEGF)Phep, |
| Gene/Transgene symbol | Avil |
Information from provider
| Provider | Paul Heppenstall |
| Provider affiliation | Adriano Buzzati-Traverso Campus, EMBL Monterotondo |
| Genetic information | iDTR cassette has been inserted into the advillin locus replacing exon 2 and 66bp upstream thereof, creating a permanent null situation. |
| Phenotypic information | When crossed with an appropriate Cre line allows Diphtheria toxin-mediated ablation of sensory neurons. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- A subpopulation of itch-sensing neurons marked by Ret and somatostatin expression.;Stantcheva Kalina K, Iovino Loredana, Dhandapani Rahul, Martinez Concepcion, Castaldi Laura, Nocchi Linda, Perlas Emerald, Portulano Carla, Pesaresi Martina, Shirlekar Kalyanee S, de Castro Reis Fernanda, Paparountas Triantafillos, Bilbao Daniel, Heppenstall Paul A, ;2016;EMBO reports;17;585-600; 26929027