C57BL/6N-Mex3a^{tm1(KOMP)Vlcg}/Cnbc

Status	Available to order
EMMA ID	EM:10410
International strain name	C57BL/6N-Mex3a^{tm1(KOMP)Vlcg}/Cnbc
Alternative name	C57BL/6N-Mex3a/Cnbc
Strain type	Targeted Mutant Strains : Knock-out
Allele/Transgene symbol	Mex3a^{tm1(KOMP)Vlcg},
Gene/Transgene symbol	Mex3a

Information from provider

Provider	Raquel Almeida
Provider affiliation	Differentiation and Cancer Group, IPATIMUP
Genetic information	This mouse line originates from KOMP ES clone 14620A-E12.
Phenotypic information	Homozygous: Potential phenotyping data in the IMPC portal Heterozygous: See above
References	MEX3A regulates Lgr5⁺ stem cell maintenance in the developing intestinal epithelium.;Pereira Bruno, Amaral Ana L, Dias Alexandre, Mendes Nuno, Muncan Vanesa, Silva Ana R, Thibert Chantal, Radu Anca G, David Leonor, Máximo Valdemar, van den Brink Gijs R, Billaud Marc, Almeida Raquel, ;2020;EMBO reports;21;e48938; 32052574
Homozygous fertile	not known
Homozygous viable	not known
Homozygous matings required	not known
Immunocompromised	not known

Information from EMMA

Archiving centre	CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain
Animals used for archiving	heterozygous C57BL/6N

Literature references

MEX3A regulates Lgr5⁺ stem cell maintenance in the developing intestinal epithelium.;Pereira Bruno, Amaral Ana L, Dias Alexandre, Mendes Nuno, Muncan Vanesa, Silva Ana R, Thibert Chantal, Radu Anca G, David Leonor, Máximo Valdemar, van den Brink Gijs R, Billaud Marc, Almeida Raquel, ;2020;EMBO reports;21;e48938; 32052574

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

Other EMMA strains

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C57BL/6N-Mex3atm1(KOMP)Vlcg/Cnbc