C57BL/6N-Cpeb3tm1a(EUCOMM)Hmgu/Cnbc

Status

Available to order

EMMA IDEM:10412
Citation informationRRID:IMSR_EM:10412 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6N-Cpeb3tm1a(EUCOMM)Hmgu/Cnbc
Alternative nameC57BL/6N-Cpeb3/Cnbc
Strain typeTargeted Mutant Strains
Allele/Transgene symbolCpeb3tm1a(EUCOMM)Hmgu
Gene/Transgene symbolCpeb3

Information from provider

ProviderRaúl Méndez
Provider affiliationIRB Barcelona
Genetic informationThis mouse line originates from EUCOMM ES clone HEPD0670_2_G03.
Phenotypic informationHomozygous:
Potential phenotyping data in the IMPC portal

Heterozygous:
see above
References
  • The RNA binding protein CPEB2 regulates hormone sensing in mammary gland development and luminal breast cancer.;Pascual Rosa, Martín Judit, Salvador Fernando, Reina Oscar, Chanes Veronica, Millanes-Romero Alba, Suñer Clara, Fernández-Miranda Gonzalo, Bartomeu Anna, Huang Yi-Shuian, Gomis Roger R, Méndez Raúl, ;2020;Science advances;6;eaax3868; 32440535
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreCNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain
Animals used for archivingheterozygous C57BL/6NHsd males

Disease and phenotype information

MGI phenotypes (gene matching)
  • increased anxiety-related response / MGI
  • hypoactivity / MGI
  • abnormal long term depression / MGI
  • reduced female fertility / MGI
  • no phenotypic analysis / MGI
  • nervous system phenotype / MGI
  • abnormal calcium ion homeostasis / MGI
  • abnormal neuron physiology / MGI
  • growth/size/body region phenotype / MGI
  • behavior/neurological phenotype / MGI
  • vision/eye phenotype / MGI
  • abnormal spatial reference memory / MGI
  • enhanced contextual conditioning behavior / MGI
  • abnormal dendritic spine morphology / MGI
  • abnormal hippocampus pyramidal cell morphology / MGI

Literature references

  • The RNA binding protein CPEB2 regulates hormone sensing in mammary gland development and luminal breast cancer.;Pascual Rosa, Martín Judit, Salvador Fernando, Reina Oscar, Chanes Veronica, Millanes-Romero Alba, Suñer Clara, Fernández-Miranda Gonzalo, Bartomeu Anna, Huang Yi-Shuian, Gomis Roger R, Méndez Raúl, ;2020;Science advances;6;eaax3868; 32440535

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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