IMPC phenotypes (gene matching)
C57BL/6N-Per2tm1c(EUCOMM)Hmgu/H
| Status | Available to order |
| EMMA ID | EM:10465 |
| Citation information | RRID:IMSR_EM:10465 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Per2tm1c(EUCOMM)Hmgu/H |
| Alternative name | HEPD0553_1_A01 |
| Strain type | Targeted Mutant Strains : Targeted Conditional |
| Allele/Transgene symbol | Per2tm1c(EUCOMM)Hmgu |
| Gene/Transgene symbol | Per2 |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This line originates from EUCOMM ES clone HEPD0553_1_A01, after breeding with a Flp recombinase deleter line to convert the original targeted allele tm1a (knock-out first allele) into a conditional allele tm1c. For further details on the construction of this clone see the page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Familial advanced sleep-phase syndrome / Orphanet_164736
MGI phenotypes (gene matching)
- salivary gland epithelial hyperplasia / MGI
- abnormal body weight / MGI
- increased body weight / MGI
- abnormal retina morphology / MGI
- pup cannibalization / MGI
- abnormal food preference / MGI
- abnormal sleep pattern / MGI
- abnormal blood vessel morphology / MGI
- increased mortality induced by gamma-irradiation / MGI
- reduced female fertility / MGI
- decreased litter size / MGI
- premature death / MGI
- no abnormal phenotype detected / MGI
- abnormal bone marrow cell morphology/development / MGI
- abnormal male preputial gland morphology / MGI
- abnormal retinal vasculature morphology / MGI
- no phenotypic analysis / MGI
- decreased cellular sensitivity to gamma-irradiation / MGI
- nervous system phenotype / MGI
- abnormal nervous system morphology / MGI
- increased incidence of tumors by ionizing radiation induction / MGI
- increased hematopoietic stem cell number / MGI
- abnormal brain wave pattern / MGI
- improved glucose tolerance / MGI
- behavior/neurological phenotype / MGI
- abnormal food intake / MGI
- abnormal maternal behavior / MGI
- abnormal basal metabolism / MGI
- early reproductive senescence / MGI
- prolonged estrous cycle / MGI
- absent estrous cycle / MGI
- abnormal pregnancy / MGI
- enhanced conditioned place preference behavior / MGI
- enhanced behavioral response to cocaine / MGI
- increased salivary gland tumor incidence / MGI
- abnormal hematopoietic stem cell physiology / MGI
- increased bone volume / MGI
- abnormal circadian temperature homeostasis / MGI
- decreased hematopoietic stem cell proliferation / MGI
- increased lymphoma incidence / MGI
- increased bone ossification / MGI
- abnormal circadian behavior / MGI
- shortened circadian behavior period / MGI
- arrhythmic circadian behavior persistence / MGI
- delayed circadian behavior phase / MGI
- abnormal locomotor circadian rhythm / MGI
- abnormal circadian sleep/wake cycle / MGI