STOCK Tg(tetO-Pax4,-DsRed)/Cnbc
| Status | Available to order |
| EMMA ID | EM:10595 |
| International strain name | STOCK Tg(tetO-Pax4,-DsRed)/Cnbc |
| Alternative name | PAX4 WT; Pax4-Tg |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(tetO-Pax4,-DsRed) |
| Gene/Transgene symbol | Tg(tetO-Pax4,-DsRed) |
Information from provider
| Provider | Benoit Gauthier |
| Provider affiliation | Stem Cells, Andalusian Canter for Molecular Biology and Regenerative Medicine (CABIMER) |
| Genetic information | Transgenic mouse with the potential to expresses the transcription factor PAX4 together with fluorescent protein DsRed ubiquitously, under the control of TRE-pCMV inducible promoter. This mouse line should be crossed with any suitable rtTA or tTA line for tissue specific expression according to expression patterns of the rtTA or the tTA additional transgene. |
| Phenotypic information | Homozygous:No particular phenotype in comparison with non-transgenic mouse. Good general health without physiologic troubles or anatomic malformations. No troubles of behavior.Heterozygous:No particular phenotype in comparison with non-transgenic mouse. Good general health without physiologic troubles or anatomic malformations. No troubles of behavior. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
| Animals used for archiving | homozygous C57BL/6J |
Literature references
- In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice.;Hu He Kai Hui, Lorenzo Petra I, Brun Thierry, Jimenez Moreno Carmen M, Aeberhard Deborah, Vallejo Ortega Jorge, Cornu Marion, Thorel Fabrizio, Gjinovci Asllan, Thorens Bernard, Herrera Pedro L, Meda Paolo, Wollheim Claes B, Gauthier Benoit R, ;2011;Diabetes;60;1705-15; 21521872