| Status | Available to order |
| EMMA ID | EM:10602 |
| Citation information | RRID:IMSR_EM:10602 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6-Atm1Brd Hnrnprtm1a(EUCOMM)Wtsi/Flmg |
| Alternative name | B6-Hnrnpr |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Hnrnprtm1a(EUCOMM)Wtsi |
| Gene/Transgene symbol | Hnrnpr |
| Provider | Michael Sendtner |
| Provider affiliation | Institute for Clinical Neurobiology, University of Würzburg |
| Genetic information | The L1L2_Bact_P cassette was inserted at position 136315880 of chromosome 4 upstream of the critical exon(s) (Build GRCm38). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon(s) at position 136316682. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele can be created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. If cre expression occurs without flp expression, a reporter knockout mouse will be created. Further information on targeting strategies used for this and other EUCOMM/KOMP alleles can be found here. |
| Phenotypic information | Homozygous:Not characterized yetHeterozygous:Not characterized yet |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
| Archiving centre | B.S.R.C. Alexander Fleming, Vari, Greece |
| Animals used for archiving | heterozygous C57BL/6 males, wild-type C57BL/6 females |
| Stage of embryos | Morula |
