C57BL/6NTac-Vgfem1(IMPC)H/H

Status

Available to order

EMMA IDEM:10784
Citation informationRRID:IMSR_EM:10784 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NTac-Vgfem1(IMPC)H/H
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolVgfem1(IMPC)H
Gene/Transgene symbolVgf

Information from provider

Provider MRC, Medical Research Council
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom
Animals used for archivingheterozygous C57BL/6NTac males
Breeding at archiving centreThis stock has been maintained on C57BL/6NTac background

Disease and phenotype information

IMPC phenotypes (allele matching)
  • tremors / IMPC
  • abnormal locomotor behavior / IMPC
  • hyperactivity / IMPC
  • increased exploration in new environment / IMPC
  • limb grasping / IMPC
  • male infertility / IMPC
  • short tibia / IMPC
  • increased circulating alanine transaminase level / IMPC
  • decreased spleen weight / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • decreased circulating glucose level / IMPC
  • increased circulating total protein level / IMPC
  • decreased prepulse inhibition / IMPC
  • increased grip strength / IMPC
  • decreased circulating fructosamine level / IMPC
IMPC phenotypes (gene matching)
  • hyperactivity / IMPC
  • limb grasping / IMPC
  • abnormal locomotor behavior / IMPC
  • increased circulating alanine transaminase level / IMPC
  • decreased prepulse inhibition / IMPC
  • increased grip strength / IMPC
  • male infertility / IMPC
  • decreased spleen weight / IMPC
  • decreased circulating glucose level / IMPC
  • decreased circulating fructosamine level / IMPC
  • tremors / IMPC
  • short tibia / IMPC
  • increased exploration in new environment / IMPC
  • increased circulating total protein level / IMPC
  • increased circulating aspartate transaminase level / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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