IMPC phenotypes (allele matching)
B6Brd;B6N-Tyrc-Brd Zfp106tm1a(KOMP)Wtsi/WtsiH
| Status | Available to order |
| EMMA ID | EM:10852 |
| International strain name | B6Brd;B6N-Tyrc-Brd Zfp106tm1a(KOMP)Wtsi/WtsiH |
| Alternative name | EPD0033_4_C03 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Zfp106tm1a(KOMP)Wtsi |
| Gene/Transgene symbol | Zfp106 |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | This mouse line originates from KOMP ES clone EPD0033_4_C03. For further details on the construction of this clone see the page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
| Animals used for archiving | heterozygous 0 |
| Breeding at archiving centre | Maintained on a C57BL/6NTac background |
Disease and phenotype information
MGI phenotypes (allele matching)
- increased circulating calcium level / MGI
- kyphosis / MGI
- tremors / MGI
- motor neuron degeneration / MGI
- abnormal spinal cord morphology / MGI
- small dorsal root ganglion / MGI
- small L4 dorsal root ganglion / MGI
- small L5 dorsal root ganglion / MGI
- weight loss / MGI
- hypoactivity / MGI
- impaired coordination / MGI
- abnormal gait / MGI
- limb grasping / MGI
- impaired limb coordination / MGI
- premature death / MGI
- abnormal muscle physiology / MGI
- gliosis / MGI
- neurodegeneration / MGI
- chromatolysis / MGI
- abnormal soleus morphology / MGI
- abnormal gastrocnemius morphology / MGI
- abnormal redox activity / MGI
- astrocytosis / MGI
- nervous system phenotype / MGI
- abnormal muscle electrophysiology / MGI
- positive geotaxis / MGI
- abnormal axon morphology / MGI
- axon degeneration / MGI
- abnormal mitochondrial physiology / MGI
- abnormal lumbar dorsal root ganglion morphology / MGI
- microgliosis / MGI
- increased variability of skeletal muscle fiber size / MGI
- centrally nucleated skeletal muscle fibers / MGI
- decreased skeletal muscle fiber number / MGI
- abnormal skeletal muscle fiber type ratio / MGI
- skeletal muscle fiber atrophy / MGI
- skeletal muscle atrophy / MGI
- skeletal muscle fibrosis / MGI
- decreased gastrocnemius weight / MGI
- decreased soleus weight / MGI
- decreased tibialis anterior weight / MGI
- decreased grip strength / MGI
- abnormal mitochondrial ATP synthesis coupled electron transport / MGI
- increased spinal cord apoptosis / MGI
- abnormal external male genitalia morphology / MGI