B6;C3H-Tg(Alb1-HCVN)35Sml/Orl
| Status | Available to order |
| EMMA ID | EM:10981 |
| Citation information | RRID:IMSR_EM:10981 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;C3H-Tg(Alb1-HCVN)35Sml/Orl |
| Alternative name | FL-N/35 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Alb1-HCVN)35Sml |
| Gene/Transgene symbol | Tg(Alb1-HCVN)35Sml |
Information from provider
| Provider | Hervé LERAT |
| Provider affiliation | IMRB, Inserm U955 Equipe 18 |
| Genetic information | Constitutive expression, limited to the liver, of all hepatitis C virus proteins. |
| Phenotypic information | Homozygous:Not studiedHeterozygous:Liver steatosis (older than 6 months) and liver cancer (older than 13 months). |
| Breeding history | Always bred as heterozygotes. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
| Animals used for archiving | heterozygous C57BL/6J males |
Literature references
- Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus.;Lerat Hervé, Honda Masao, Beard Michael R, Loesch Kim, Sun Jiaren, Yang Yan, Okuda Michiari, Gosert Rainer, Xiao Shu-Yuan, Weinman Steven A, Lemon Stanley M, ;2002;Gastroenterology;122;352-65; 11832450