C57BL/6N-Elk3em1(IMPC)Ics/Ics

Status

Available to order

EMMA IDEM:11041
Citation informationRRID:IMSR_EM:11041 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6N-Elk3em1(IMPC)Ics/Ics
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolElk3em1(IMPC)Ics
Gene/Transgene symbolElk3

Information from provider

Provider ICS, Institut Clinique de la Souris
Provider affiliationICS, Institut Clinique de la Souris
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France

Disease and phenotype information

IMPC phenotypes (allele matching)
  • increased circulating HDL cholesterol level / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • increased circulating cholesterol level / IMPC
IMPC phenotypes (gene matching)
  • decreased prepulse inhibition / IMPC
  • abnormal retina blood vessel pattern / IMPC
  • abnormal eye morphology / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • increased circulating HDL cholesterol level / IMPC
  • increased circulating cholesterol level / IMPC
  • abnormal retina vasculature morphology / IMPC
MGI phenotypes (gene matching)
  • abnormal blood vessel physiology / MGI
  • hypoactivity / MGI
  • abnormal cardiovascular system physiology / MGI
  • respiratory failure / MGI
  • respiratory distress / MGI
  • premature death / MGI
  • abnormal retinal vasculature morphology / MGI
  • no phenotypic analysis / MGI
  • chylothorax / MGI
  • lymphangiectasis / MGI
  • cardiovascular system phenotype / MGI
  • vision/eye phenotype / MGI
  • decreased angiogenesis / MGI
  • abnormal vascular endothelial cell morphology / MGI
  • abnormal retinal blood vessel morphology / MGI
  • abnormal pleura morphology / MGI
  • postnatal lethality, incomplete penetrance / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

Right strain for your research?

The information provided on this page is, to the best of EMMA’s knowledge, based on data supplied by the original provider. End users are responsible for reviewing these details and for validating the strain and its suitability for their experimental use.​
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