B6N.Cg-Mapkapk2tm1c(EUCOMM)Hmgu/Biat
Status | Available to order |
EMMA ID | EM:11549 |
International strain name | B6N.Cg-Mapkapk2tm1c(EUCOMM)Hmgu/Biat |
Alternative name | C57BL/6N-Mapkapk2 |
Strain type | Targeted Mutant Strains : Conditional mutation |
Allele/Transgene symbol | Mapkapk2tm1c(EUCOMM)Hmgu, |
Gene/Transgene symbol | Mapkapk2 |
Information from provider
Provider | Alexander Dohnal |
Provider affiliation | Tumor Immunology, St. Anna Kinderkrebsforschung |
Genetic information | Mapkapk2tm1a(EUCOMM)Hmgu/H mice (EMMA strain EM:05658; EUCOMM clone HEPD0672_2_A02) were crossed with B6.129S4-Gt(ROSA)26Sortm1(FLP1)Dym/RainJ for flp recombinase-mediated deletion and production of conditional MK2 (or Mapkapk2) knock-out mice. |
Phenotypic information | Homozygous:noneHeterozygous:none |
References |
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Homozygous fertile | yes |
Homozygous viable | yes |
Homozygous matings required | no |
Immunocompromised | no |
Information from EMMA
Archiving centre | University of Veterinary Medicine, Vienna, Austria |
Literature references
- The MAPK-Activated Kinase MK2 Attenuates Dendritic Cell-Mediated Th1 Differentiation and Autoimmune Encephalomyelitis.;Soukup Klara, Halfmann Angela, Le Bras Marie, Sahin Emine, Vittori Sarah, Poyer Fiona, Schuh Cornelia, Luger Romana, Niederreiter Birgit, Haider Thomas, Stoiber Dagmar, Blüml Stephan, Schabbauer Gernot, Kotlyarov Alexey, Gaestel Matthias, Felzmann Thomas, Dohnal Alexander M, ;2015;Journal of immunology (Baltimore, Md. : 1950);195;541-52; 26078274
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