IMPC phenotypes (allele matching)
C57BL/6N-Brd2em1(IMPC)Wtsi/WtsiIeg
| Status | Available to order |
| EMMA ID | EM:11572 |
| Citation information | RRID:IMSR_EM:11572 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Brd2em1(IMPC)Wtsi/WtsiIeg |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Brd2em1(IMPC)Wtsi |
| Gene/Transgene symbol | Brd2 |
Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Disease and phenotype information
IMPC phenotypes (gene matching)
MGI phenotypes (gene matching)
- abnormal adipose tissue morphology / MGI
- abnormal vertebral body morphology / MGI
- rib bifurcation / MGI
- rib fusion / MGI
- scoliosis / MGI
- enlarged heart / MGI
- abnormal interatrial septum morphology / MGI
- double outlet right ventricle / MGI
- abnormal cell death / MGI
- decreased cell proliferation / MGI
- abnormal craniofacial morphology / MGI
- increased rib number / MGI
- enlarged liver sinusoidal spaces / MGI
- abnormal pineal gland morphology / MGI
- small thymus / MGI
- abnormal forebrain morphology / MGI
- abnormal embryonic neuroepithelial layer differentiation / MGI
- abnormal choroid plexus morphology / MGI
- exencephaly / MGI
- absent superior cervical ganglion / MGI
- abnormal vagus ganglion morphology / MGI
- obese / MGI
- abnormal eating behavior / MGI
- increased circulating triglyceride level / MGI
- abnormal embryo size / MGI
- decreased embryo size / MGI
- hemorrhage / MGI
- increased circulating insulin level / MGI
- abnormal neural tube morphology / MGI
- abnormal nasal septum morphology / MGI
- hepatic steatosis / MGI
- persistent truncus arteriosis / MGI
- increased circulating glucagon level / MGI
- abnormal semilunar valve morphology / MGI
- abnormal aortic valve morphology / MGI
- abnormal pulmonary valve morphology / MGI
- small thyroid gland / MGI
- small kidney / MGI
- abnormal cell cycle / MGI
- aphakia / MGI
- decreased rib number / MGI
- aorta coarctation / MGI
- increased pancreatic beta cell number / MGI
- abnormal neural tube closure / MGI
- abnormal circulating lipid level / MGI
- embryonic growth retardation / MGI
- thin myocardium compact layer / MGI
- transposition of great arteries / MGI
- abnormal respiratory quotient / MGI
- retroesophageal right subclavian artery / MGI
- abnormal adenohypophysis morphology / MGI
- fetal growth retardation / MGI
- abnormal embryonic neuroepithelium morphology / MGI
- abnormal optic stalk morphology / MGI
- abnormal optic cup morphology / MGI
- basisphenoid bone foramen / MGI
- absent vagus nerve / MGI
- abnormal vertebral arch morphology / MGI
- absent vertebral arch / MGI
- fusion of vertebral arches / MGI
- increased adiponectin level / MGI
- abnormal gallbladder morphology / MGI
- abnormal middle ear ossicle morphology / MGI
- increased circulating cholesterol level / MGI
- abnormal pancreatic islet morphology / MGI
- abnormal olfactory nerve morphology / MGI
- improved glucose tolerance / MGI
- pancreatic islet hyperplasia / MGI
- decreased circulating glucose level / MGI
- increased circulating leptin level / MGI
- increased fat cell size / MGI
- artery stenosis / MGI
- increased circulating tumor necrosis factor level / MGI
- increased circulating interleukin-1 beta level / MGI
- thoracoschisis / MGI
- increased basal metabolism / MGI
- increased pancreatic islet number / MGI
- increased epididymal fat pad weight / MGI
- increased interscapular fat pad weight / MGI
- abnormal blood homeostasis / MGI
- abnormal optic chiasm morphology / MGI
- increased total body fat amount / MGI
- atrioventricular septal defect / MGI
- perimembraneous ventricular septal defect / MGI
- muscular ventricular septal defect / MGI
- abnormal pectinate muscle morphology / MGI
- persistent right dorsal aorta / MGI
- common truncal valve / MGI
- abnormal lung position or orientation / MGI
- postnatal lethality, incomplete penetrance / MGI
- perinatal lethality, incomplete penetrance / MGI
- embryonic lethality during organogenesis, complete penetrance / MGI
- enlarged brain ventricles / MGI
- interrupted aortic arch, type b / MGI
- dual inferior vena cava / MGI
- myelocele / MGI
- increased embryonic neuroepithelium apoptosis / MGI
- increased embryonic neuroepithelium thickness / MGI
- abnormal common carotid artery morphology / MGI
- increased embryonic tissue cell apoptosis / MGI
- absent pectinate muscle / MGI
- abnormal hepatic portal vein connection / MGI
- abnormal hypoglossal nerve topology / MGI
- retropleural edema / MGI
- subcutaneous edema / MGI
- abnormal Mullerian duct topology / MGI
- abnormal ductus venosus morphology / MGI
- abnormal ductus venosus topology / MGI
- duplication of ductus venosus / MGI
- absent costovertebral joint / MGI
- absent eye muscles / MGI
- abnormal thymus topology / MGI
- reduced sympathetic cervical ganglion size / MGI
- absent connection between subcutaneous lymph vessels and lymph sac / MGI
- blood in lymph vessels / MGI
- abnormal umbilical vein topology / MGI
- abnormal external carotid artery origin / MGI
- abnormal vertebral artery topology / MGI
- heterochrony / MGI
- abnormal brain artery topology / MGI
- persistent trigeminal artery / MGI
- abnormal physiological umbilical hernia morphology / MGI