- increased mean corpuscular hemoglobin / IMPC
- increased CD4-positive, alpha beta T cell number / IMPC
- decreased CD8-positive, alpha-beta T cell number / IMPC
- decreased mature B cell number / IMPC
- preweaning lethality, complete penetrance / IMPC
- increased or absent threshold for auditory brainstem response / IMPC
- decreased KLRG1+ CD8 alpha beta T cell number / IMPC
C57BL/6N-Brd2em1(IMPC)Wtsi/WtsiIeg
Status | Available to order |
EMMA ID | EM:11572 |
International strain name | C57BL/6N-Brd2em1(IMPC)Wtsi/WtsiIeg |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Brd2em1(IMPC)Wtsi |
Gene/Transgene symbol | Brd2 |
Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Disease and phenotype information
IMPC phenotypes (allele matching)
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