Sprague Dawley rat Rno1_Del(Sult1a1-Spn)/YahIcsOrl

Status	Available to order
EMMA ID	EM:11821
Citation information	EM:11821
International strain name	Sprague Dawley rat Rno1_Del(Sult1a1-Spn)/YahIcsOrl
Alternative name	Sprague Dawley rat Rno1_Del(Sult1a1-Spn)
Strain type	Endonuclease-mediated
Allele/Transgene symbol	rat Rno1 Del(Sult1a1-Spn)
Gene/Transgene symbol	rat Del (Sult1a1-Spn)

Information from provider

Provider	Yann HERAULT
Provider affiliation	Translational Medicine and Neurogenetics, I.G.B.M.C.
Genetic information	Sprague Dawley rat. Deletion of the genetic interval Sult1a1-Spn: we targeted an extended sequence of the whole locus from one allele and the CRISPR/Cas9 system allowed us to remove the region encompassing 28 genes, orthologous to human.
Phenotypic information	Homozygous: Homozygous rat not generated Heterozygous: Growth delay and hyperactive behaviour
Breeding history	1 backcross on Sprague Dawley genetic background
References	None available
Homozygous fertile	not known
Homozygous viable	not known
Homozygous matings required	no
Immunocompromised	no

Information from EMMA

Archiving centre	Institut de Transgenose, INTRAGENE, Orléans, France
Animals used for archiving	heterozygous rat Sprague-Dawley males, wild-type rat Sprague-Dawley females
Stage of embryos	2-cell

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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