Sprague Dawley rat Rno1_Dup(Sult1a1-Spn)/YahIcsOrl
| Status | Available to order |
| EMMA ID | EM:11822 |
| Citation information | EM:11822 |
| International strain name | Sprague Dawley rat Rno1_Dup(Sult1a1-Spn)/YahIcsOrl |
| Alternative name | Sprague Dawley rat Rno1_Dup(Sult1a1-Spn) |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | rat Rno1 Dup(Sult1a1-Spn) |
| Gene/Transgene symbol | rat Dup (Sult1a1-Spn) |
Information from provider
| Provider | Yann HERAULT |
| Provider affiliation | Translational Medicine and Neurogenetics, I.G.B.M.C. |
| Genetic information | Sprague Dawley rat. Tandem duplication of the genetic interval between Sult1a1 and Spn genes using CRISPR/Cas9 engineering. We targeted the genetic interval borders from one allele and the CRISPR/Cas9 system allowed us to cut and transpose those sequences to the same locus on the second allele. |
| Phenotypic information | Homozygous:Not generatedHeterozygous:Overweight and hypoactivity |
| Breeding history | 1 backcross on Sprague Dawley background |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
| Animals used for archiving | heterozygous rat Sprague-Dawley males, wild-type rat Sprague-Dawley females |
| Stage of embryos | 2-cell |