FVB/NIco-Tg(Pcp2/Jun)18Dcrl/Cnrm
| Status | Available to order |
| EMMA ID | EM:00120 |
| International strain name | FVB/NIco-Tg(Pcp2/Jun)18Dcrl/Cnrm |
| Alternative name | L7-c-jun-Tg |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Pcp2/Jun)18Dcrl, |
| Gene/Transgene symbol | Tg(Pcp2/Jun)18Dcrl |
Information from provider
| Provider | Daniela Carulli |
| Provider affiliation | DIP. DI NEUROSCIENZE, Univ. di Torino |
| Phenotypic information | To generate the L7-c-Jun hybrid transgene the c-Jun cDNA was inserted into a vector named L7deltaAUG. This vector includes 1 kb of the Pcp2 (or L7) gene promoter, the L7 4 exons and 3 introns, and 200 bp downstream the TGA stop codon of the L7 gene, from which the normal and all potential ATGs were removed. The c-Jun cDNA was inserted into the unique BamHI site in the 4th exon of the L7 gene. No major defect so far detected. |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- Regenerative and survival capabilities of Purkinje cells overexpressing c-Jun.;Carulli Daniela, Buffo Annalisa, Botta Cristina, Altruda Fiorella, Strata Piergiorgio, ;2002;The European journal of neuroscience;16;105-18; 12153535