- decreased bone mineral density / IMPC
- decreased circulating LDL cholesterol level / IMPC
- decreased circulating HDL cholesterol level / IMPC
- decreased body weight / IMPC
- increased circulating free fatty acid level / IMPC
- abnormal vibrissa morphology / IMPC
- decreased IgE level / IMPC
- decreased circulating triglyceride level / IMPC
- decreased hemoglobin content / IMPC
- decreased circulating alanine transaminase level / IMPC
- increased circulating alkaline phosphatase level / IMPC
- increased lean body mass / IMPC
- abnormal behavior / IMPC
- decreased T cell number / IMPC
- decreased circulating cholesterol level / IMPC
- abnormal response to tactile stimuli / IMPC
- decreased circulating serum albumin level / IMPC
- increased circulating total protein level / IMPC
- decreased circulating aspartate transaminase level / IMPC
- increased mature B cell number / IMPC
- decreased IgG1 level / IMPC
- decreased total body fat amount / IMPC
C57BL/6NTac-Arhgef4tm1a(KOMP)Wtsi/Wtsi
Status | Available to order |
EMMA ID | EM:12046 |
International strain name | C57BL/6NTac-Arhgef4tm1a(KOMP)Wtsi/Wtsi |
Alternative name | EPD0135_1_A05 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Arhgef4tm1a(KOMP)Wtsi, |
Gene/Transgene symbol | Arhgef4 |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from KOMP ES clone EPD0135_1_A05. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Wellcome Trust Sanger Institute, Hinxton, United Kingdom |
Animals used for archiving | homozygous C57BL/6N, wild-type C57BL/6N |
Stage of embryos | 2-cell |
Disease and phenotype information
IMPC phenotypes (allele matching)
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