- decreased bone mineral density / IMPC
- abnormal cranium morphology / IMPC
- abnormal snout morphology / IMPC
- abnormal mandible morphology / IMPC
- decreased body length / IMPC
- decreased body weight / IMPC
- abnormal tooth morphology / IMPC
- abnormal joint morphology / IMPC
- decreased circulating alanine transaminase level / IMPC
- decreased lean body mass / IMPC
- abnormal incisor morphology / IMPC
- decreased circulating aspartate transaminase level / IMPC
- absent pinna reflex / IMPC
- decreased total body fat amount / IMPC
- decreased bone mineral content / IMPC
- decreased effector memory CD8-positive, alpha-beta T cell number / IMPC
- preweaning lethality, incomplete penetrance / IMPC
B6Brd;B6N-Tyrc-Brd Slc25a21tm1a(KOMP)Wtsi/Wtsi
Status | Available to order |
EMMA ID | EM:12127 |
International strain name | B6Brd;B6N-Tyrc-Brd Slc25a21tm1a(KOMP)Wtsi/Wtsi |
Alternative name | EPD0085_1_D04 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Slc25a21tm1a(KOMP)Wtsi, |
Gene/Transgene symbol | Slc25a21 |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from KOMP ES clone EPD0085_1_D04. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Wellcome Trust Sanger Institute, Hinxton, United Kingdom |
Animals used for archiving | heterozygous C57BL/6Brd-Tyr |
Disease and phenotype information
IMPC phenotypes (allele matching)
MGI phenotypes (allele matching)
- decreased circulating LDL cholesterol level / MGI
- abnormal cranium morphology / MGI
- abnormal snout morphology / MGI
- abnormal mandible morphology / MGI
- decreased body length / MGI
- decreased body weight / MGI
- abnormal tooth morphology / MGI
- abnormal joint morphology / MGI
- decreased circulating alanine transaminase level / MGI
- abnormal incisor morphology / MGI
- decreased circulating potassium level / MGI
- decreased circulating aspartate transaminase level / MGI
- absent pinna reflex / MGI
- decreased total body fat amount / MGI
- decreased bone mineral content / MGI
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