C57BL/6-Dbhtm1a(EUCOMM)Wtsi/Cnbc
Status | Available to order |
EMMA ID | EM:12233 |
International strain name | C57BL/6-Dbhtm1a(EUCOMM)Wtsi/Cnbc |
Alternative name | Dbhtm1a(EUCOMM)Wtsi |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Dbhtm1a(EUCOMM)Wtsi, |
Gene/Transgene symbol | Dbh |
Information from provider
Provider | Miguel Soares |
Provider affiliation | Biomedicine, LAIMM - Faculty of Medicine of Porto, Portugal |
Genetic information | Gene targeted: Dbh (dopamine beta hydroxylase; MGI:94864). Knockout first mice (KOMP tm1a allele; reporter-tagged insertion with conditional potential). |
Phenotypic information | Homozygous:http://www.informatics.jax.org/marker/phenotypes/MGI:94864Heterozygous:no abnormal phenotype detected |
Breeding history | 10+ generations. First backcrosses (not with parents but with unrelated C57BL/6J animals), then intercrosses (avoided consanguinity). |
References | None available |
Homozygous fertile | not known |
Homozygous viable | no |
Homozygous matings required | no |
Immunocompromised | no |
Information from EMMA
Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
Animals used for archiving | heterozygous C57BL/6J |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Dopamine beta-hydroxylase deficiency / Orphanet_230
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