- decreased leukocyte cell number / IMPC
- abnormal heart morphology / IMPC
- enlarged heart / IMPC
- abnormal spleen morphology / IMPC
- enlarged spleen / IMPC
- abnormal uterus morphology / IMPC
- anophthalmia / IMPC
- decreased locomotor activity / IMPC
- decreased exploration in new environment / IMPC
- abnormal skin morphology / IMPC
- abnormal eye morphology / IMPC
- increased circulating alkaline phosphatase level / IMPC
- increased kidney weight / IMPC
- enlarged uterus / IMPC
- decreased lymphocyte cell number / IMPC
- increased cardiac muscle contractility / IMPC
- decreased CD8-positive, alpha-beta T cell number / IMPC
- enhanced cued conditioning behavior / IMPC
- decreased grip strength / IMPC
- dilated aorta / IMPC
- increased fasting circulating glucose level / IMPC
C57BL/6NCrl-Asb7em1(IMPC)Ccpcz/Ph
Status | Available to order |
EMMA ID | EM:12241 |
Citation information | RRID:IMSR_EM:12241 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | C57BL/6NCrl-Asb7em1(IMPC)Ccpcz/Ph |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Asb7em1(IMPC)Ccpcz |
Gene/Transgene symbol | Asb7 |
Information from provider
Provider | Institute of Molecular Genetics |
Provider affiliation | Department of Transgenic Models of Diseases, Institute of Molecular Genetics |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
Animals used for archiving | heterozygous C57BL/6NCrl males |
Disease and phenotype information
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- decreased lymphocyte cell number / IMPC
- decreased grip strength / IMPC
- increased fasting circulating glucose level / IMPC
- abnormal heart morphology / IMPC
- abnormal eye morphology / IMPC
- increased circulating alkaline phosphatase level / IMPC
- anophthalmia / IMPC
- enlarged heart / IMPC
- abnormal spleen morphology / IMPC
- decreased locomotor activity / IMPC
- abnormal uterus morphology / IMPC
- increased cardiac muscle contractility / IMPC
- enlarged spleen / IMPC
- dilated aorta / IMPC
- decreased exploration in new environment / IMPC
- decreased leukocyte cell number / IMPC
- abnormal skin morphology / IMPC
- enhanced cued conditioning behavior / IMPC
- increased kidney weight / IMPC
- enlarged uterus / IMPC
- decreased CD8-positive, alpha-beta T cell number / IMPC
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