- lordosis / IMPC
- abnormal liver morphology / IMPC
- enlarged liver / IMPC
- abnormal spleen morphology / IMPC
- enlarged spleen / IMPC
- abnormal thymus morphology / IMPC
- enlarged thymus / IMPC
- abnormal kidney morphology / IMPC
- increased kidney weight / IMPC
- increased circulating total protein level / IMPC
- decreased circulating potassium level / IMPC
- increased CD4-positive, alpha-beta T cell number / IMPC
- increased T-helper cell number / IMPC
C57BL/6NCrl-Pstpip1em1(IMPC)Ccpcz/Ph
Status | Available to order |
EMMA ID | EM:12284 |
Citation information | RRID:IMSR_EM:12284 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | C57BL/6NCrl-Pstpip1em1(IMPC)Ccpcz/Ph |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Pstpip1em1(IMPC)Ccpcz |
Gene/Transgene symbol | Pstpip1 |
Information from provider
Provider | Institute of Molecular Genetics |
Provider affiliation | Department of Transgenic Models of Diseases, Institute of Molecular Genetics |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
Animals used for archiving | heterozygous C57BL/6NCrl males |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Pyogenic arthritis-pyoderma gangrenosum-acne syndrome / Orphanet_69126
- Hyperzincemia and hypercalprotectinemia / Orphanet_251523
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- increased CD4-positive, alpha-beta T cell number / IMPC
- decreased circulating potassium level / IMPC
- enlarged liver / IMPC
- enlarged spleen / IMPC
- abnormal liver morphology / IMPC
- lordosis / IMPC
- increased kidney weight / IMPC
- abnormal kidney morphology / IMPC
- increased circulating total protein level / IMPC
- increased T-helper cell number / IMPC
- enlarged thymus / IMPC
- abnormal spleen morphology / IMPC
- abnormal thymus morphology / IMPC
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