STOCK Cfap157tm1d(EUCOMM)Hmgu/Biat
| Status | Available to order |
| EMMA ID | EM:12396 |
| Citation information | RRID:IMSR_EM:12396 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Cfap157tm1d(EUCOMM)Hmgu/Biat |
| Alternative name | Cfap157-delta-ex2 generated from Cfap157tm1a(EUCOMM)Hmgu |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Cfap157tm1d(EUCOMM)Hmgu |
| Gene/Transgene symbol | Cfap157 |
Information from provider
| Provider | Achim Gossler |
| Provider affiliation | MHH |
| Genetic information | cre recombinase-mediated germline deletion of exon 2, null allele |
| Phenotypic information | Homozygous:Immotile spermHeterozygous:No phenotype |
| Breeding history | Germ-line chimera bred to Tg(Zp3-cre) on a mixed genetic background (C57BL/6; 129Sv; CD1). Further breeding on this background. |
| References |
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| Homozygous fertile | females only |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | University of Veterinary Medicine, Vienna, Austria |
| Animals used for archiving | heterozygous Other (please specify below) males |
Literature references
- CFAP157 is a murine downstream effector of FOXJ1 that is specifically required for flagellum morphogenesis and sperm motility.;Weidemann Marina, Schuster-Gossler Karin, Stauber Michael, Wrede Christoph, Hegermann Jan, Ott Tim, Boldt Karsten, Beyer Tina, Serth Katrin, Kremmer Elisabeth, Blum Martin, Ueffing Marius, Gossler Achim, ;2016;Development (Cambridge, England);143;4736-4748; 27965440