- kyphosis / IMPC
- abnormal thyroid gland morphology / IMPC
- abnormal spleen morphology / IMPC
- decreased body weight / IMPC
- abnormal skin morphology / IMPC
- abnormal kidney morphology / IMPC
- increased circulating alkaline phosphatase level / IMPC
- abnormal spine curvature / IMPC
- enlarged thyroid gland / IMPC
- decreased grip strength / IMPC
- preweaning lethality, incomplete penetrance / IMPC
C57BL/6NCrl-Fgf14em1(IMPC)Ccpcz/Ph
Status | Available to order |
EMMA ID | EM:12410 |
Citation information | RRID:IMSR_EM:12410 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | C57BL/6NCrl-Fgf14em1(IMPC)Ccpcz/Ph |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Fgf14em1(IMPC)Ccpcz |
Gene/Transgene symbol | Fgf14 |
Information from provider
Provider | Institute of Molecular Genetics |
Provider affiliation | Department of Transgenic Models of Diseases, Institute of Molecular Genetics |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
Animals used for archiving | heterozygous C57BL/6NCrl males |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Spinocerebellar ataxia type 27 / Orphanet_98764
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- decreased grip strength / IMPC
- abnormal kidney morphology / IMPC
- abnormal thyroid gland morphology / IMPC
- abnormal skin morphology / IMPC
- kyphosis / IMPC
- abnormal spleen morphology / IMPC
- preweaning lethality, incomplete penetrance / IMPC
- decreased body weight / IMPC
- increased circulating alkaline phosphatase level / IMPC
- enlarged thyroid gland / IMPC
- abnormal spine curvature / IMPC
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