C57BL/6NCrl-Zc3h8em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:12493
Citation informationRRID:IMSR_EM:12493 

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International strain nameC57BL/6NCrl-Zc3h8em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolZc3h8em1(IMPC)Ccpcz
Gene/Transgene symbolZc3h8

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

IMPC phenotypes (allele matching)
  • lordosis / IMPC
  • abnormal heart morphology / IMPC
  • enlarged heart / IMPC
  • abnormal liver morphology / IMPC
  • enlarged liver / IMPC
  • abnormal spleen morphology / IMPC
  • enlarged spleen / IMPC
  • abnormal skin morphology / IMPC
  • abnormal digit morphology / IMPC
  • abnormal kidney morphology / IMPC
  • enlarged kidney / IMPC
  • single kidney / IMPC
  • abnormal auditory brainstem response / IMPC
  • preweaning lethality, complete penetrance / IMPC
  • embryonic lethality prior to organogenesis / IMPC
  • embryonic lethality prior to tooth bud stage / IMPC
  • decreased CD8-positive, naive alpha-beta T cell number / IMPC
IMPC phenotypes (gene matching)
  • single kidney / IMPC
  • preweaning lethality, complete penetrance / IMPC
  • enlarged spleen / IMPC
  • lordosis / IMPC
  • abnormal skin morphology / IMPC
  • enlarged liver / IMPC
  • abnormal heart morphology / IMPC
  • abnormal digit morphology / IMPC
  • abnormal auditory brainstem response / IMPC
  • enlarged heart / IMPC
  • embryonic lethality prior to tooth bud stage / IMPC
  • abnormal kidney morphology / IMPC
  • decreased CD8-positive, naive alpha-beta T cell number / IMPC
  • enlarged kidney / IMPC
  • embryonic lethality prior to organogenesis / IMPC
  • abnormal liver morphology / IMPC
  • abnormal spleen morphology / IMPC

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Register interest

Availabilities

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    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

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