C57BL/6NCrl-Fam221aem1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:12622
Citation informationRRID:IMSR_EM:12622 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Fam221aem1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolFam221aem1(IMPC)Ccpcz
Gene/Transgene symbolFam221a

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

IMPC phenotypes (allele matching)
  • kyphosis / IMPC
  • increased neutrophil cell number / IMPC
  • abnormal heart morphology / IMPC
  • enlarged heart / IMPC
  • enlarged lymph nodes / IMPC
  • abnormal testis morphology / IMPC
  • small testis / IMPC
  • abnormal eye morphology / IMPC
  • abnormal lymph node morphology / IMPC
  • increased hematocrit / IMPC
  • increased erythrocyte cell number / IMPC
  • abnormal spine curvature / IMPC
  • increased circulating glucose level / IMPC
  • increased circulating total protein level / IMPC
  • increased airway resistance / IMPC
  • increased CD8-positive, naive alpha-beta T cell number / IMPC
IMPC phenotypes (gene matching)
  • small testis / IMPC
  • increased airway resistance / IMPC
  • increased erythrocyte cell number / IMPC
  • abnormal spine curvature / IMPC
  • increased CD8-positive, naive alpha-beta T cell number / IMPC
  • abnormal testis morphology / IMPC
  • increased neutrophil cell number / IMPC
  • increased hematocrit / IMPC
  • abnormal heart morphology / IMPC
  • abnormal lymph node morphology / IMPC
  • increased circulating glucose level / IMPC
  • enlarged heart / IMPC
  • kyphosis / IMPC
  • abnormal eye morphology / IMPC
  • increased circulating total protein level / IMPC
  • enlarged lymph nodes / IMPC

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Register interest

Availabilities

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    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

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